The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care."After two breakdowns I started having severe panic attacks and stopped leaving the house altogether. After 6 months of this awfulness I was prescribed Zoloft and I’ve been on Zoloft for over 15 years. I am taking 100mg per day and up to 200mg during a stressful event. Zoloft has been the only drug that keeps me balanced and gives me the ability to function and hold down a full time job for the past 10 years. On top of that my throat felt like I was trying to swallow cotton and I had a heart rate of 115. But this wasn’t my only treatment and what has made me stay well is being engaged with my psychiatrist weekly for 3 years and now only when I need him.""I started 25mg of Zoloft last night. Trembling and shaking I felt like I was going to die. Once it subsided I realized I either had an awful reaction or my first full blown panic attack. Panic disorder is a common psychiatric condition with significant associated morbidity and disability. Both psychopharmacologic agents and cognitive-behavioral therapies have been shown to be successful treatments. Recent research has promoted selective serotonin reuptake inhibitors (SSRIs) as first-line therapy for panic disorder, specifically sertraline, because of its effectiveness in treating depression and obsessive-compulsive disorder. Pollack and associates conducted a randomized, double-blind, flexible-dose study to determine the effectiveness of varying dosages of sertraline in the treatment of patients with panic disorder. Patients eligible for the study were at least 18 years of age and met the criteria for panic disorder, with or without agoraphobia, as defined by the (DSM-III-R). They had to have experienced panic attacks before the study and during a two-week placebo washout period before treatment commenced. In addition, patients in the study had a minimum score of 18 on the Hamilton Anxiety Scale and no signs of substantial depression.
Risks and benefits of medications for panic disorder: a comparison of SSRIs and benzodiazepines. Is the efficacy of antidepressants in panic disorder mediated by adverse events? Cochrane Database of Systematic Reviews, Bighelli, Irene Borghesani, Anna Barbui, Corrado and Hayley, Shawn 2017. Antidepressants versus placebo for panic disorder in adults. Bighelli, Irene Castellazzi, Mariasole Cipriani, Andrea Girlanda, Francesca Guaiana, Giuseppe Koesters, Markus Turrini, Giulia Furukawa, Toshi A and Barbui, Corrado 2018. INFLUENCE OF STUDY DESIGN ON TREATMENT RESPONSE IN ANXIETY DISORDER CLINICAL TRIALS. Acute hemodynamic effects of a selective serotonin reuptake inhibitor in postural tachycardia syndrome: A randomized, crossover trial. Mar, Philip L Raj, Vidya Black, Bonnie K Biaggioni, Italo Shibao, Cyndya A Paranjape, Sachin Y Dupont, William D Robertson, David and Raj, Satish R 2014. Sertraline is a type of antidepressant known as a selective serotonin reuptake inhibitor (SSRI). It's often used to treat depression, and also sometimes panic attacks, obsessive compulsive disorder (OCD) and post-traumatic stress disorder (PTSD). Sertraline helps many people recover from depression, and has fewer unwanted side effects than older antidepressants. Sertraline comes as tablets, which are available only on prescription. Sertraline can be taken by adults for depression or obsessive compulsive disorder. Sertraline can be taken by children aged 6 to 17, but only for obsessive compulsive disorder. Check with your doctor before starting to take sertraline if you: If you have diabetes, sertraline can make it more difficult to keep your blood sugar stable. You can choose to take sertraline at any time, as long as you stick to the same time every day.
Also known as: Zoloft The following information is NOT intended to endorse drugs or recommend therapy. Started 2 weeks ago on 25 mg setraline and immediately saw small hints of change. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care."Took it for around 6 months for anxiety. Pushed through to see if they would go away, but no luck. Don't get me wrong, the side effects we're brutal: brain fog, suicidal thoughts, headaches, major anxiety.. But hearing myself laughing and singing in the midst of it all were strangely foreign and lovely at the same time. I’ve tried nearly all SSRIs""I sigh as I write these words as a couple days ago it was I who was reading these reviews, desperate for help. I was prescribed 0.5 mg ativan on an as needed basis and it has helped somewhat in calming the initial side effects. Tried upping to 50 mg after one week and couldn't move from exhaustion. I will stay at 25 mg for a while and keep my fingers crossed that things only get better. ""I have always had general anxiety managed w/ cognitive behavioral therapy, but stressful events led to me experiencing debilitating panic attacks. I had been avoiding SSRIs for years but finally agreed to start. JAMAJAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Facial Plastic Surgery JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Pollack MHSmoller JW Pharmacologic approaches to treatment-resistant panic disorder. Pollack MHOtto MWRosenbaum JFeds Challenges in Clinical Practice Pharmacologic and Psychosocial Strategies New York, NY Guilford Press1996;89- 112Google Scholar Oehrberg SChristiansen PEBehnke KBorup ALSeverin BSoegaard JCalberg HJudge ROhrstrom JKManniche PM Paroxetine in the treatment of panic disorder: a randomized, double-blind, placebo-controlled study. 1995;167374- 379Google Scholar Den Boer JAWestenberg JGM Effect of a serotonin and noradrenaline uptake inhibitor in panic disorder: a double-blind comparative study with fluvoxamine and maprotiline. 1988;359- 74Google Scholar Sharp DMPower KGSimpson RJSimpson VMoodie EAnstee JAAshford JJ Fluvoxamine, placebo and cognitive behavior therapy used alone and in combination in the treatment of panic disorder and agoraphobia. 1996;10219- 242Google Scholar Reimherr FWByerley WFWard MFLebegue BJWender PH Sertraline, a selective inhibitor of serotonin uptake, for the treatment of outpatients with major depressive disorder. 1988;24200- 205Google Scholar Greist JChouinard GDu Boff EHalaris AKim SWKoran LLiebowitz MLydiard RBRasmussen SWhite KSikes C Double-blind parallel comparison of three dosages of sertraline and placebo in outpatients with obsessive-compulsive disorder. 1995;52289- 295Google Scholar Clark DMSalkovskis PMHackmann AMiddleton HPavlos AGelder M A comparison of cognitive therapy, applied relaxation and imipramine in the treatment of panic disorder. 1994;164759- 769Google Scholar Tesar GERosenbaum JFPollack MHOtto MWSachs GSHerman JBCohen LSSpier SA Double-blind, placebo-controlled comparison of clonazepam and alprazolam for panic disorder.
NHS medicines information on sertraline - what it's used for, side effects. Some people who take sertraline for panic attacks find their anxiety gets worse during. Reviews and ratings for sertraline when used in the treatment of panic disorder. 335 reviews submitted.