Duloxetine was approved for the treatment of major depression in 2004. While duloxetine has demonstrated improvement in depression-related symptoms compared to placebo, comparisons of duloxetine to other antidepressant medications have been less successful. A 2012 Cochrane Review did not find greater efficacy of duloxetine compared to SSRIs and newer antidepressants. Additionally, the review found evidence that duloxetine has increased side effects and reduced tolerability compared to other antidepressants. It thus did not recommend duloxetine as a first line treatment for major depressive disorder, given the (then) high cost of duloxetine compared to inexpensive off-patent antidepressants and lack of increased efficacy. do not list duloxetine among the recommended treatment options. A review from the Annals of Internal Medicine lists duloxetine among the first line drug treatments, however, along with citalopram, escitalopram, sertraline, paroxetine, and venlafaxine. Antidepressant medications are used to treat a variety of conditions, including depression and other mental/mood disorders. These medications can help prevent suicidal thoughts/attempts and provide other important benefits. However, a small number of people (especially people younger than 25) who take antidepressants for any condition may experience worsening depression, other mental/mood symptoms, or suicidal thoughts/attempts. Therefore, it is very important to talk with the doctor about the risks and benefits of antidepressant medication (especially for people younger than 25), even if treatment is not for a mental/mood condition. Tell the doctor right away if you notice worsening depression/other psychiatric conditions, unusual behavior changes (including possible suicidal thoughts/attempts), or other mental/mood changes (including new/worsening anxiety, panic attacks, trouble sleeping, irritability, hostile/angry feelings, impulsive actions, severe restlessness, very rapid speech). Be especially watchful for these symptoms when a new antidepressant is started or when the dose is changed. Show More Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain).
A generic version of Cymbalta has been approved by the FDA. However, this does not mean that the product will necessarily be commercially available - possibly because of drug patents and/or drug exclusivity. The following products are equivalent to Cymbalta and have been approved by the FDA: Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Cymbalta. These medications may be counterfeit and potentially unsafe. Patent and Trademark Office at any time during a drug's development and may include a wide range of claims. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication. Chemical Name DULOXETINE (doo-LOX-e-teen)CYMBALTA is a prescription serotonin-norepinephrine reuptake inhibitor (SNRI) medication effectively used for the treatment of major depressive disorder (MDD) and generalized anxiety disorder (GAD) mental depression. It is also used for pain caused by nerve damage associated with diabetes, diabetic peripheral neuropathic pain, fibromyalgia and chronic musculoskeletal pain due to chronic osteoarthritis pain and chronic low back pain. IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. Some patients may think CYMBALTA can be used for stress urinary incontinence; however the FDA failed the approval due to concerns over liver toxicity and suicidal events. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. In contrast, it is approved for this purpose in Europe, where it is used as an Take CYMBALTA exactly as directed by your health professional. See your health care professional for medical advice and treatment. A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body. The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg.
Drug Information on Cymbalta, Irenka duloxetine includes drug pictures, side effects, drug interactions, directions for use, symptoms of overdose, and what to avoid. Duloxetine is contraindicated for concomitant use in patients receiving MAOI therapy, due to the risk for serotonin syndrome. Duloxetine is a serotonin norepinephrine reuptake inhibitor SNRI and should not be used concurrently with MAOI therapy or within 14 days of discontinuation of a MAOI intended to treat a psychiatric disorder.