Clomid is a widely used ovulation induction drug and is frequently a first-line fertility treatment for women who do not ovulate. Lack of ovulation (anovulation) is one of the most common causes for infertility. Once successful ovulation is achieved, fertility is often restored. Clomid is sucessful in inducing ovulation in about 80% of women. If this dose does not produce eggs, then the dose can be increased to 100 mg. Clomid often produces more than one egg per cycle (super ovulation). Clomid can result in the creation of so many eggs that we will recommend that you avoid conception in that cycle (hyperstimulation). Ultimately, about half of these women will get pregnant. It works by increasing levels of follicle stimulation hormone (FSH). Despite this, the success rate per cycle is 10-20%. An ultrasound will determine how many eggs you have made in each cycle. If you have made too many eggs, we will advise you to avoid conception. In rare cases Clomid can make so many eggs that you will need to suspend your fertility program and use a birth control pill for three months to calm the ovaries down. About one in four women will not ovulate when taking Clomid. Sometimes, the reason you may not ovulate on Clomid is because the dosage is too low. It's common to start Clomid treatment at 50 mg, and then increase to 100 mg if you don't respond. In some cases, doctors will try doses up to 250 mg. However, if you're still not ovulating even at higher dosages, this is referred to as Clomid resistance. PCOS: Women with PCOS commonly have trouble with Clomid resistance, especially those who are diagnosed as insulin resistant or with hyperandrogenic levels (high levels of DHEAs and male hormone levels). For women with PCOS, treatment with the insulin resistance drug metformin, also known as Glucophage, may help.
My OB said he's not going to trigger me this month, my first cycle on clomid and it makes me want to strangle him. I have my follicle scan on. Has anyone taking clomid and successfully ovulated without the trigger shot? My doctor doesn't want me to take the trigger because I have to many follicles that.