Chronic severe heart failure is frequently associated with disturbances in the central control of breathing. During wakefulness, central breathing disorders could be ameliorated with beta-blocker treatment, but nothing is known about the effects of beta-blockers on the control of breathing during sleep. This study intends to determinate the prevalence and severity of nocturnal apnoeas and hypopnoeas in heart failure patients treated with or without metoprolol or carvedilol. Fifty consecutive patients with dilated cardiomyopathy in NYHA class II–IV with a left ventricular ejection fraction (LVEF) of 35% or below were studied with full polysomnography over one night. Sleep is an innate and essential part of human life. Various aspects of sleep are negatively affected by beta-blockers. We compared the impact of two beta-blockers, metoprolol succinate (extended release) and nebivolol, on sleep quality in patients with stage 1 hypertension. This was a prospective, randomized, open-label, parallel-group study. Eligible patients were administered the Pittsburgh Sleep Quality Index (PSQI) questionnaire by a blinded interviewer and were randomized to receive metoprolol (starting dose 25 mg) or nebivolol (starting dose 2.5 mg) once daily for 6 weeks. The first dose was administered before patients left the clinic. Visits were scheduled for 1, 2, 4, and 6 weeks after the initiation of therapy.
Hi Guys, Had quarterly follow-up with my electrophysiologist on 2/18. Have you ever changed from one Beta Blocker to another, and what is the transition like? The only thing that seems to help me is a good dose of potassium in my diet. He had increased my Nadolol from 40mg to 60mg a day back in November and by Christmas I was so sluggish and bound up I didn't feel like I could function any more. I was on the Toprol for awhile and then the doc switched me out to antenolol.only significant thing that really bothered me was that the Toprol (metoprolol) really made me super tired so we switched out to the antenolol which was a great fit for me. I cut back to 40mg and was able to poo and get out of bed again. The warnings on the Nadolol aren't nearly so terrifying as this med. Bypeep i am just commenting to make sure you don't add any potassium to your diet w/out clearing it w. Lopressor is a widely prescribed, easily tolerated by most beta blocker. LOL So, after hearing this my electrophysiologist told me that he rarely treats anyone with Nadolol anymore (I've been on it since I was 14, and that was 22 years ago) because it's an older-style beta-blocker. My biggest fear is that it won't control my NSVT like the Nadolol does and I'll have breakthroughs. your doc..extra load of it can cause rhythm issues if your electrolyte balance is thrown out of whack...i am sure others will weigh in on the Toprol tho its a pretty common med..........luck w. My cardiologist once quipt that with our lifestyle and diet today, that everyone should be on this along with a statin, and in fact there is already a combination pill available. He told me that he wanted to switch me to Metoprolol, which acts more directly on the heart and not other organs. Metoprolol comes to in two varieties; metoprolol tartrate, and metoprolol succinate, the later has a time release property. 25 used to control them fairly well, but not anymore. Mark Im on 100mg of metoprolol and don't experience any side effects- not to suggest the drug is actually reducing my episodes of SVT either. My PAC's and PVC's, are back with a vengeance, so I'm taking 75mg a day. Before taking metoprolol, tell your doctor if you have congestive heart failure, low blood pressure, circulation problems, pheochromocytoma, asthma or other breathing problems, diabetes, depression, liver or kidney disease, a thyroid disorder, or severe allergies. Metoprolol is only part of a complete program of treatment for hypertension that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely if you are being treated for hypertension. If you are being treated for high blood pressure, keep using this medication even if you feel well. You may need to use blood pressure medication for the rest of your life. Metoprolol is in a group of drugs called beta-blockers. Beta-blockers affect the heart and circulation (blood flow through arteries and veins). A Toprol XL tablet can be divided in half if your doctor has told you to do so. Metoprolol is used to treat angina (chest pain) and hypertension (high blood pressure). Metoprolol may also be used for other purposes not listed in this medication guide. Do not take in larger or smaller amounts or for longer than recommended. The half tablet should be swallowed whole, without chewing or crushing.
Various aspects of sleep are negatively affected by beta-blockers. We compared the impact of two beta-blockers, metoprolol succinate extended release and. The arousal index, sleep quality, and daytime sleepiness were improved in. of metoprolol or carvedilol is associated with a lower prevalence and severity of.