Oceans offer enormous biological diversity with unique metabolic and physiological capabilities that ensure survival in diverse habitats and the potential to produce an enormous diversity of metabolites not found in terrestrial organisms.” This is paraphrase of the rationale that is used at the beginning of almost any marine drug discovery venture. I have written stuff like this myself, try but I have a problem with it. While the inherent diversity and uniqueness of marine life is true and this is almost certainly matched by chemical diversity, is this enough to form the basis of a drug discovery venture? Yes – If you have an unlimited supply of money and no fixed timelines. In the real world we need more than the big picture to develop a proposition for a drug discovery venture that has realistic chance of success. Marine natural products drug discovery is bioprospecting, which like any kind of prospecting, should not be a completely random process. Before we start looking for gold we need to know where is a good place to look, we need to know how to look, we need to know what we are looking for, and we need to know that someone will buy it if we find it. What does this mean for marine drug discovery: What to look for? Finasteride is a drug used to treat male pattern hair loss, a common condition that involves hair thinning on the scalp that often leads to a receding hair line or balding on the crown of your head. It affects some men from 20 years old and is more common as men age, affecting the majority of males at some stage throughout their life. Finasteride is the generic name of the drug and is the active ingredient in the medication that works to reduce hair loss. Finasteride is the active ingredient in Propecia and is available in a generic, unbranded tablet. Finasteride and Propecia are medically equivalent but Finasteride is available at a much lower cost. Generic medicines contain the same active ingredient and are equally effective and medically equivalent as the branded products but are available at a lower price. Generic manufacturers have to demonstrate that they are medically identical to the branded product - i.e.
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