Mineralocorticoids (aldosterone) are so named because they are important in maintaining electrolyte homeostasis. However, mineralocorticoids also trigger a broader range of functions in nonclassic target cellular sites, including some effects on wound healing after injury. In addition, a chronic and inappropriate (relative to intravascular volume and dietary sodium intake) increase in aldosterone secretion evokes a wound healing response in the absence of tissue injury. This can lead to antialdosterone (eg, , decrease synthesis of interleukins and numerous other proinflammatory cytokines, suppress cell-mediated immunity, reduce complement synthesis, and decrease production and activity of leukocytes. Unsurprisingly then, glucocorticoids are by far the most efficacious anti-inflammatory drugs. They are also the most commonly used anti-inflammatory drugs. However, because their pharmacologic and physiologic effects are so broad, the potential for adverse effects is considerable. Depo-Medrone may be used locally or systemically, particularly where oral therapy is not feasible. Depo-Medrone may be used by any of the following routes: intramuscular, intra-articular, periarticular, intrabursal, intralesional or into the tendon sheath. It Depo-Medrone should not be mixed with any other suspending agent or solution. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever suspension and container permit. Depo-Medrone may be used by any of the following routes: intramuscular, intra-articular, periarticular, intrabursal, intralesional and into the tendon sheath. It must not be used by the intrathecal or intravenous routes (see sections 4.3 and 4.8). Undesirable effects may be minimised by using the lowest effective dose for the minimum period (see section 4.4).
It is one of the more commonly used long-acting cortisone injectable products. One of the more common uses is to give long-lasting relief from allergic itching. Allergies are a malfunction of the body's defenses, so you give enough cortisone to suppress the body's defenses a little. You inject a blob of this stuff into the dog's thigh muscle. The bigger the blob, the higher the blood level of drug. So, when you first give it, the blood level of drug is very high. As time goes by, the blob gets smaller and smaller, so the blood level gets lower and lower. Eventually, the blood level gets low enough that it won't suppress the itching anymore. The problem is this: you never know what the blood level actually is and how much is left. DEPO-MEDROL used for allergic conditions: Relieves itching and inflammation of allergic dermatitis, acute moist dermatitis, dry eczema, urticaria, bronchial sensitivities, and otitis externa in dogs, cats & horses. We Ship Monday through Friday Only - Orders Placed after 2 PM EST might not be shipped until the following business day. Orders placed on weekends or holidays will not be shipped until the next business day. Please allow 2-3 days additional for vet approval for orders that include prescription items, or items out of stock. DEPO-MEDROL used for allergic conditions by relieving itching and inflammation of allergic dermatitis, acute moist dermatitis, dry eczema, urticaria, bronchial sensitivities, and otitis externa in dogs,it is also used for Musculoskeletal Conditions like treating traumatic arthritis, osteoarthritis and generalized arthritic conditions in dogs, cats & horses. Useful when it is desirable to reduce inflammation, vascularization, fibroblastic infiltration and scar tissue. Indicated for snakebite due to its antitoxemic, anti-inflammatory and antishock activity.
Known for it's anti-inflammatory effects Depo-Medrol 20 mg/m L, 20 m L is an injectable steroid for dogs, cats and horses useful for allergic reactions, overwhelming infections and pain associated with diseases like arthritis. We Ship Monday through Friday Only - Orders Placed after 2 PM EST might not be shipped until the following business day. Orders placed on weekends or holidays will not be shipped until the next business day. Please allow 2-3 days additional for vet approval for orders that include prescription items, or items out of stock. Depo-Medrol 20 mg/m L, 20 m L is an injectable steroid for dogs, cats, and horses with powerful anti-inflammatory effects. Depo-Medrol (methylprednisolone) pet meds are used to reduce pain and lameness associated with arthritis, synovitis, tendonitis, and other musculoskeletal conditions. Allergic reactions and overwhelming infections are also treated with Depo-Medrol steroids. Depo-Medrol is a powerful anti-inflammatory steroid medication in injectable form for the treatment of allergic conditions, arthritis, and other problems. It may also be used to suppress the immune system during times of acute illness or in animals suffering from autoimmune disorders. Depo-Medrol is fast acting and works for longer periods than prednisolone or prednisone. Use this medication only as directed by your veterinarian. Consult your veterinarian about the proper technique for administering injectable medications. Do not differ from the dosing schedule given by your veterinarian. The duration of treatment depends on the animal and condition being treated, the severity of illness, and the individual response. When stopping long-term use, reduce the dose gradually to avoid potentially serious withdrawal effects.
DEPO-MEDROL® 40 mg/mL Suspension for Injection. 2. The lowest possible dose of corticosteroid should be used to control the condition under treatment. As with other adrenal steroids, DEPO-MEDROL Sterile Aqueous Suspension has been found useful in alleviating the. Injections of methylprednisolone acetate have been well tolerated. The average intramuscular dose for dogs is 20 mg.