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    The active component of the medicine reversibly selectively inhibits the cycle guanosine monophosphate (c GMP) that is the specific phosphodiesterase type 5 (PDE5). The local release of NO is registered during the sexual stimulation, and at the same time the specific phosphodiesterase of type 5 activity inhibition leads to the cycle guanosine monophosphate level increase in the corpus cavernosum. Due to tadalafil the smooth muscle tonus decrease and the penile blood inflow increase take place that stimulate erection. Tadalafil does not influence the sexual stimulation. The effect of tadalafil on other phosphodiesterases is insignificant so Cialis does not affect the cardiovascular system, the liver function, skeletal muscle and other organs. Tadalafil does not change the qualitative characteristics of sperm, does not change the level of testosterone, follicle-stimulating and luteinizing hormone in the blood. The effect of the medicine Cialis is possible only under condition of sexual stimulation. There are currently three so-called “erection pills” on the market: Viagra, Cialis and Levitra. All are available on prescription only, to treat erectile dysfunction (ED). It’s a powerful potency-enhancing pill, but needs to be taken almost immediately before sex. Cialis came later, but has the great advantage that it works for up to 36 hours. The latest variant, Cialis Once a Day, is the only pill that gives you back a completely normal sex life. Taken daily, it restores erectile function on a permanent basis. So that you’re ready for intercourse whenever you need to be. Cialis Once a Day is the latest development in the market for erection pills.

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    The daily pill stays effective in between doses, but may take 4 to 5 days before it begins working. The “weekender” version of Cialis can start working in as little as 30 minutes for men who take the highest dose of the drug (20mgs); it stays effective in the body for up for 36 hours. Avoid heavy drinking (5 glasses of wine or 5 shots of whiskey); when combined with Cialis, it can lead to headaches, dizziness, an increase in heart rate, and a drop in blood pressure. Take 1 hour before sex, although many men report erections in 20 to 30 minutes. Because Staxyn comes in a sleek black package and is taken as a rapidly dissolving tablet (without water), some men think of it as a more discrete way to treat ED. Prescribing information now recommends taking it 30 minutes before sex. Some men, however, report results in as little as 10 to 12 minutes, depending on the dose. Because of these findings, Auxilium Pharmaceuticals, the Chesterbrook, Pa., company that has U. marketing rights to the drug, has asked the May be taken with or without food, and with a moderate amount of alcohol (3 drinks). Some men with erectile dysfunction, or ED, find they can return to an active sex life by treating an underlying condition, such as high blood pressure, or with counseling and lifestyle changes. But others find they may need medication to get and keep an erection. The FDA has approved several prescription drugs you take orally to treat ED. These medications all work similarly to each other. However, there are subtle differences in how long they stay effective and how quickly they begin to work. Levitra takes about 30 minutes to start working and the effects last a little longer than Viagra, about 5 hours. It contains the same active ingredient as Levitra and can begin working in about 15 minutes. Viagra takes around 30 minutes to become effective and lasts about 4 hours.

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  5. Oct 20, 2014. Cialis Tadalafil drug is used to treat erectile dysfunction. It is also prescribed under the name Adcirca for treatment of pulmonary arterial.

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