Antifungal, in the same drug family as ketoconazole and itraconazole. Fluconazole has many advantages over the other antifungal drugs including the option of oral administration. Fluconazole is a first-generation triazole antifungal medication. It differs from earlier azole antifungals (such as ketoconazole) in that its structure contains a triazole ring instead of an imidazole ring. While the imidazole antifungals are mainly used topically, fluconazole and certain other triazole antifungals are preferred when systemic treatment is required because of their improved safety and predictable absorption when administered orally. Fluconazole's spectrum of activity includes most Candida species (but not Candida krusei or Candida glabrata), Cryptococcus neoformans, some dimorphic fungi, and dermatophytes, among others. Common uses include: Fungal resistance to drugs in the azole class tends to occur gradually over the course of prolonged drug therapy, resulting in clinical failure in immunocompromised patients (e.g., patients with advanced HIV receiving treatment for thrush or esophageal Candida infection). albicans, resistance occurs by way of mutations in the ERG11 gene, which codes for 14α-demethylase. These mutations prevent the azole drug from binding, while still allowing binding of the enzyme's natural substrate, lanosterol. glabrata is increasing the rate of efflux of the azole drug from the cell, by both ATP-binding cassette and major facilitator superfamily transporters. Development of resistance to one azole in this way will confer resistance to all drugs in the class. Other gene mutations are also known to contribute to development of resistance. What store can i buy retin a How to purchase retin a Canadian Brand Name. CanesOral; Descriptions. Fluconazole is used to treat serious fungal or yeast infections, such as vaginal candidiasis. Lists the various brand names available for medicines containing fluconazole. Find information on fluconazole use, treatment, drug class and molecular formula. Structure, properties, spectra, suppliers and links for Fluconazole, Diflucan, 86386-73-4. Read the Patient Information Leaflet if available from your pharmacist before you start taking fluconazole and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth with or without food as directed by your doctor, usually once daily. If you are taking the liquid suspension form of this medication, shake the bottle well before each dose. Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose. Dosage is based on your medical condition and response to treatment. Generally in children, the dose should not exceed 600 milligrams daily unless directed by the doctor. On December 19, 2018, Pfizer announced a joint merger of their consumer healthcare division with UK pharma giant Glaxo Smith Kline; the British company will maintain a controlling share (listed at 68%). The company develops and produces medicines and vaccines for a wide range of medical disciplines, including immunology, oncology, cardiology, endocrinology, and neurology. Its products include the blockbuster drug Lipitor (atorvastatin), used to lower LDL blood cholesterol; Lyrica (pregabalin) for neuropathic pain and fibromyalgia; Diflucan (fluconazole), an oral antifungal medication; Zithromax (azithromycin), an antibiotic; Viagra (sildenafil) for erectile dysfunction; and Celebrex (also Celebra, celecoxib), an anti-inflammatory drug. was expected to merge with Allergan, Plc to create the Ireland-based "Pfizer plc" in a deal that would have been worth $160 billion. Pfizer was founded in 1849 by German-American Charles Pfizer and his cousin Charles F. They launched the chemicals business Charles Pfizer and Company from a building at the intersection of Harrison Avenue and Bartlett Street in Williamsburg, Brooklyn, where they produced an antiparasitic called santonin. This was an immediate success, although it was the production of citric acid that really kick-started Pfizer's growth in the 1880s. Pfizer continued to buy property to expand its lab and factory on the block bounded by Bartlett Street, Harrison Avenue, Gerry Street, and Flushing Avenue. Pfizer's original administrative headquarters was at 81 Maiden Lane in Manhattan. Fluconazole trade name MATERIAL SAFETY DATA SHEET -, Fluconazole - brand name list from Metoprolol blood sugarBuy viagra new zealandRoaccutane 20mg buy onlineBuy lexapro online ukLasix push Brand Name. Composition. Company. Packing. MRP Rs. ADOCON cap. Fluconazole 150mg. adoc pharma. 1. 15.00. af-400 tab. Fluconazole 400mg. MEDLINE INDIA - FLUCONAZOLE. Fluconazole C13H12F2N6O ChemSpider. Fluconazole - Trade Names - Medindia. Brand Name Contains Dosage Form Manufacturer PriceTk. AFLUZOLE Fluconazole 50mg & 150mg/capsule Capsule Ambee Pharmaceuticals Ltd. 50mg x 30s pack 240.00. Fluconazole. Brand names/Manufacturer Many manufacturers/Brand names. AFUNGIL Senosiain - MEXICO; APO-FLUCONAZOLE Apotex, CANADA. Fluconazole is an Azole Antifungal. The mechanism of action of fluconazole is as a Cytochrome P450 2C19 Inhibitor, and Cytochrome P450 3A4 Inhibitor, and Cytochrome.