It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Dose of chloroquine for malaria treatment Methotrexate and folic acid and plaquenil Chloroquine overdose Plaquenil is also indicated for the treatment of chronic discoid lupus erythematosus and systemic lupus erythematosus in adults, and for the treatment of acute and chronic rheumatoid arthritis in adults. • Postmarketing cases of life-threatening and fatal cardiomyopathy have been reported with use of Plaquenil and chloroquine. Use of PLAQUENIL in patients with psoriasis may precipitate a severe attack of psoriasis. When used in patients with porphyria the condition may be exacerbated. The preparation should not be used in these conditions unless in the judgment of the physician the benefit to the patient outweighs the possible hazard. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine -sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Uses for plaquenil Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects., PLAQUENIL® What happens when you take plaquenil with out having lupus Find information about which conditions Plaquenil Oral is commonly used to treat. What Conditions does Plaquenil Treat? - WebMD. Hydroxychloroquine - Wikipedia. Hydroxychloroquine Side Effects, Dosage, Uses, and More. I'm on Plaquenil for leukocytoclastic vasculitis among other autoimmune problems. Is this why Plaquenil is thought to be effective in treating this? I keep hearing about the vascular problems with the virus and autoimmune drug intervention, but I'm confused about the intent behind the medicine. Aug 14, 2017 Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. Jun 30, 2015 Plaquenil is a prescription medication used to prevent and treat certain types of malaria. It is also approved for the treatment of systemic lupus erythematosus SLE, and rheumatoid arthritis. This medication may be prescribed for other uses.