Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. What is safe dosage of plaquenil for lupus Vision loss with plaquenil Does plaquenil make you sleepy Hydroxychloroquine 200 mg tablet It seems like it took about 7 or 8 months for the Plaquenil 200mg 2x daily to.these medications including all of my cholesterol medications cause constipation so I follow a bowel regimen using sena and colace and sometimes MOM on bad nights and it works well for the most part. Hi I think that Lucy may be correct in that the constipation may be caused from your Lupus. Normally, Plaquenil causes the opposite effect with diarrhea being the problem. I've not heard of anyone mentioning constipation as the side effect. That's not to say it doesn't happen though. I would contact your Rheumy and see what they have to say. Most common side effects people have besides Constipation * Fatigue feeling of tiredness 206 people, 39.85%. Diarrhea 168 people, 32.50%. Nausea feeling of having an urge to vomit 162 people, 31.33%. Pain 152 people, 29.40%. Joint Pain 137 people, 26.50%. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil side effects constipation Plaquenil Indications, Side Effects, Warnings -, Bad Side Effects of Plaquenil - How many hours does plaquenil work in the body Plaquenil Side Effects by Likelihood and Severity INFREQUENT side effects. If experienced, these tend to have a Severe expression. A Disorder Of The Retina Of The Eye;. RARE side effects. Common and Rare Side Effects for Plaquenil Oral. Will you have Constipation with Plaquenil - eHealthMe. Hydroxychloroquine Oral Uses, Side Effects, Interactions.. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Plaquenil “ Side Effects Severe abdominal pain, bloating, constipation. Increased leg spasms @ night. Hair loss, accelerated depression. At the 4th week, itchy, red dots appear along with scalp itching. ” Aug 14, 2017 Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks.