Less than 50% of pregnancies in women with lupus have complications, but all lupus pregnancies are considered high-risk. Lupus can complicate pregnancy with an increased risk of miscarriage, premature delivery, and preeclampsia, as well as heart problems in the baby. Gabapentin interactions with plaquenil Plaquenil for rheumatoid arthritis mayo clinic It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis or juvenile idiopathic arthritis. Hydroxychloroquine in Lupus Pregnancy Megan E. B. Clowse,1 Laurence Magder,2 Frank Witter,3 and Michelle Petri3 Objective. Hydroxychloroquine HCQ is often needed to manage disease activity in systemic lupus erythematosus SLE during pregnancy. The purpose of this study was to examine lupus activity and pregnancy OBJECTIVE To study maternal and fetal outcome of pregnancy in patients with lupus who were exposed to hydroxychloroquine HCQ. “Preconception counseling allows women who have lupus to discuss their personal health with their doctor to assess risks based on how lupus has affected her thus far,” says Larry Matsumoto, MD, maternal fetal specialist at Atlanta Perinatal Consultants. If you have lupus and are considering having a baby, consider these tips to ensure a safe pregnancy and healthy baby. Hydroxychloroquine in lupus pregnancy Hydroxychloroquine Use in Lupus Patients during Pregnancy., Hydroxychloroquine in Lupus Pregnancy Treatment chloroquine resistant malariaChloroquine resistant malaria definitionDefine 4 hydroxychloroquineChloroquine phosphate suspensionPrimaquine chloroquine dosage Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus. Treating Lupus with Anti-Malarial Drugs Johns Hopkins.. Hydroxychloroquine and lupus pregnancy review of a series.. Hydroxychloroquine in lupus pregnancy - Clowse - 2006.. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Important information. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking this medicine and call your doctor at once if you. Summary. SLE is a multi-organ autoimmune disease that affects women of childbearing age. Renal involvement in the form of either active lupus nephritis LN at the time of conception, or a LN new onset or flare during pregnancy increases the risks of preterm delivery, pre-eclampsia, maternal mortality, fetal/neonatal demise, and intrauterine growth restriction. Maternal lupus is associated with adverse maternal and fetal events; however, pregnancy outcomes may be improved if conception does not occur until the disease has been inactive for ≥6 months. Hydroxychloroquine is one of the medications recommended for the management of lupus and lupus nephritis in pregnant women.