It is a disabling and painful condition which can lead to substantial loss of mobility due to pain and joint destruction. I really liked the Arava, but I I am now on MTX and Simponi now. The disease is also systemic in that it often also affects many extra-articular tissues throughout the body including the skin, blood vessels, heart, lungs, and... I was on the Orencia when I was on the above two you mentioned. Hydroxychloroquine plaquenil and surgery Plaquenil price australia Plaquenil and juvenile arthritis Compare Arava vs. Plaquenil, which is better for uses like RA and Arthritis. Compare head-to-head ratings, side effects, warnings, dosages, interactions and patient reviews. Patients rated Plaquenil 3.7/5 over Arava 3.2/5 in overall satisfaction. Over time, leflunomide can reduce the inflammation that makes your joints painful, swollen and stiff. When you’re first prescribed leflunomide, your rheumatologist roo-ma-tolo-jist will monitor your progress. Once they feel your condition has improved, your rheumatologist will probably ask your GP to manage your treatment and prescriptions. I was on Plaquenil and Arava, plus Orencia for a bit last year, till I finally went off the Plaquenil, which wasn't working. My enzymes went up a slight bit in the beginning and then settled down. It did not affect me nearly as badly as mthx. I was on that for 9 years, and my enzymes got so high I had to stop. The doctor then kept me on my plaquenil and added Leflunomide (Arava) to replace the methotrexate. I started out on the Plaquenil and Methotrexate oral and while my RA symptoms were reduced some, the methotrexate made me extremely ill for 2 days after I took each dose. Arava and plaquenil together Rheumatoid Arthritis Drug Treatments Pros and Cons., Leflunomide Side-effects, uses, time to work Is retinal toxicity from plaquenil reversiblePlaquenil rheumatoid arthritis side effectsPlaquenil e depressioneChloroquine retrovirus production Nov 26, 2007 Drug Combos Effective Against Rheumatoid Arthritis. Older and newer medicine together often bring relief, study finds. Please note This article was published more than one year ago. The facts and conclusions presented may have since changed and may no longer be accurate. And "More information" links may no longer work. Drug Combos Effective Against Rheumatoid Arthritis. Arava AND Plaquenil for RA. DailyStrength. ARAVA with Humira -. WebMD provides information about interactions between Arava Oral and leflunomide-warfarin. These medicines may cause some risk when taken together. Contact your healthcare professional e.g. Hi Polly, I'm on all 3. I am doing well enough to walk & participate in an exercise class 3 times a week. I get the occasional pain or flare, but I've gotten to a good place by taking all 3 meds. I take plaquenil daily, Arava/leflunomide on Tues & Fri's, and Methotrexate 8 on Sundays. And I go to an opthamologist twice a year, per my Dr's. So while having RA and MS together is possible, it is not common. Q2. My best friend has been diagnosed with rheumatoid arthritis and suffers with severe pain much of the time.