Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil and low neutrophils How to code long term use plaquenil Treatment of cutaneous lupus erythematosus with acitretin and hydroxychloroquine Compare hydroxychloroquine prices Plaquenil can damage the retina of the eye. This can lead to blindness. This problem is most common when high doses are taken for a long time. If you will be taking Plaquenil for a while, it is recommended to have a thorough eye exam before starting it and every three months while taking it. The liver is highly efficient at removing ammonia from the blood. The urea cycle takes place within the mitochondria and the cytosol of hepatocytes. It relies on a number of enzymes that you may recall from medical school, such as ornithine transcarbamylase and carbamoyl phosphate synthase. Elevated liver enzymes are a common problem in some patients being treated with hydroxychloroquine, such as patients with lupus. However, as a general rule, hydroxychloroquine is not associated with an elevation in liver enzymes when used to treat autoimmune and rheumatologic diseases. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil liver enzymes Elevated liver enzymes - Mayo Clinic, Hyperammonemia Is It the Liver or Something Else? Plaquenil rpPlaquenil alternatives lupusCalcium and plaquenilIcd 10 coding for plaquenil useEffects of plaquenil on skin Plaquenil can cause serious liver or heart problems, especially if you use certain medicines at the same time, including other medicines to treat malaria; an antibiotic or antifungal medicine; Plaquenil Uses, Dosage & Side Effects -. Hydroxychloroquine Plaquenil Success, Reviews and Side.. Will you have Liver function test abnormal with Plaquenil.. I to have been taking plaquenil for at least 6 to 8 months not sure a lil lupie lol anyway and i do feel a difference in my eyes plus my liver enzymes are up i believe that the highest is 47 and mines is 48 the doc says not dangerously high but we need to keep an eye on it. im not sure but i thought that the enzymes were up cuz of the prednisone but now ill have to ask the doc. i too want. Hydroxychloroquine sulfate is a colorless crystalline solid, soluble in water to at least 20 percent; chemically the drug is 2-4-7-Chloro-4-quinolylaminopentylethylamino ethanol sulfate 11. PLAQUENIL hydroxychloroquine sulfate tablets contain 200 mg hydroxychloroquine sulfate, equivalent to 155 mg base, and are for oral administration. Plaquenil was originally approved by the Food and Drug Administration FDA in 1955. Plaquenil Warnings. Before taking Plaquenil, tell your doctor if you have or have ever had Liver disease.