Sildenafil pah

Discussion in 'Canadian Pharmacy Meds' started by fomka, 29-Aug-2019.

  1. mantanabum Well-Known Member

    Sildenafil pah


    If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist. Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following: Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Revatio PO: 5 mg or 20 mg 3 times daily, administered 4-6 hours apart IV: 2.5-mg or 10-mg bolus 3 times daily if patient is temporarily unable to take PO Recommended PO/IV dose not to be exceeded Adding Revatio to bosentan does not have any beneficial effect on exercise capacity Not to be prescribed to children (1-17 years) for pulmonary arterial hypertension (PAH); this recommendation against use is based on long-term clinical pediatric trial showing that children taking high doses had higher risk of death than children taking low doses and that low doses were not effective in improving exercise ability (see Cautions) Elicits vasodilatory properties, resulting in mild and transient decreases in blood pressure Use with caution in patients with anatomic deformation of penis (eg, angulation, cavernosal fibrosis, or Peyronie disease), conditions potentially predisposing to priapism (eg, sickle cell anemia, multiple myeloma, or leukemia), cardiovascular disease, bleeding disorders, active peptic ulcer disease, liver disease, renal impairment, multidrug antihypertensive regimens, retinitis pigmentosa, concomitant use of CYP3A4 inhibitors Pulmonary vasodilators may significantly worsen cardiovascular status of patients with pulmonary veno-occlusive disease Patient taking alpha blocker should be stabilized before starting phosphodiesterase (PDE)-5 inhibitor, which should be initiated at lowest dose; if patient is already taking optimized dose of PDE-5 inhibitor, alpha blocker should be initated at lowest dose to avoid hypotension Not to be taken with other PDE-5 inhibitors Sudden decrease or loss of hearing, which may be accompanied by tinnitus and dizziness Viagra: Patients should stop sildenafil and seek medical care if a sudden loss of vision occurs in 1 or both eyes, which could be a sign of nonarteritic anterior ischemic optic neuropathy (NAION); use with caution, and only when the anticipated benefits outweigh the risks, in patients with a history of NAION; patients with a ”crowded” optic disc may also be at an increased risk of NAION; advise patients to seek immediate medical attention in the event of a sudden loss of vision Viagra: Potential for cardiac risk with sexual activity in patients with preexisting cardiovascular disease; therefore, treatment for erectile dysfunction generally should not be instituted in men for whom sexual activity is inadvisable because of their underlying cardiovascular status May cause dose-related impairment of color discrimination; use caution in patients with retinitis pigmentosa Evaluate underlying causes of erectile dysfunction or BPH before initiating therapy Revatio: In small, prematurely terminated study of patients with PAH secondary to sickle-cell disease, vaso-occlusive crises requiring hospitalization were more commonly reported by patients who received sildenafil than by those randomized to placebo; effectiveness of sildenafil in PAH secondary to sickle-cell anemia has not been established; the clinical relevance to men treated for erectile dysfunction with sildenafil is not known Revatio: Not for use in children with PAH; increased mortality with increasing doses (hazard ratio 3.5) was observed in randomized, double-blind, placebo-controlled clinical trial of 234 children (1-17 years) with PAH who had mild-to-moderate symptoms at baseline Revatio: Epistaxis occurred in 13% of patients with PAH secondary to connective tissue disease (eg, scleroderma); this effect was not seen in idiopathic PAH; incidence was also higher in those receiving concomitant PO vitamin K antagonist therapy (9%) than in those not receiving such therapy (2%) Limited published data from randomized controlled trials, case-controlled trials, and case series do not report a clear association with sildenafil and major birth defects, miscarriage, or adverse maternal or fetal outcomes when sildenafil is used during pregnancy; there are risks to mother and fetus from untreated pulmonary arterial hypertension Pregnant women with untreated pulmonary arterial hypertension are at risk for heart failure, stroke, preterm delivery, and maternal and fetal death Limited published data from a case report describe presence of sildenafil and its active metabolite in human milk; there is insufficient information about effects of sildenafil on breastfed infant and no information on effects of sildenafil on milk production; limited clinical data during lactation preclude a clear determination of risk of drug to an infant during lactation The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

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    This study assessed the safety and patient satisfaction with conversion from sildenafil to tadalafil. METHODS In this multicenter, prospective, 6-month study, patients with PAH were instructed to take their last dose of sildenafil in the evening and initiate tadalafil 40 mg/d the next morning. Sildenafil is an oral medication called a phosphodiesterase-5 PDE5 inhibitor approved for the treatment of pulmonary arterial hypertension PAH in World Health Organization WHO Group 1 patients. The goal of this therapy is to improve exercise ability and delay clinical worsening. Sildenafil contains sildenafil, which is the same medicine found in another drug called REVATIO. REVATIO is used to treat a rare disease called pulmonary arterial hypertension PAH. Sildenafil should not be used with REVATIO or with other PAH treatments containing sildenafil or any other PDE5 inhibitors such as Adcirca tadalafil

    Citrato de sildenafila ou simplesmente sildenafil é um fármaco que é vendido sob os nomes de Viagra (usado no tratamento da disfunção eréctil no homem – impotência sexual) e Revatio (usado no tratamento da hipertensão arterial pulmonar). No caso do viagra, tem a apresentação de um diamante na cor azul niágara. Medicamento pioneiro na moderna terapêutica da disfunção eréctil masculina, foi sintetizado originalmente pelo Laboratório Farmacêutico Pfizer. Seus principais concorrentes no mercado de medicamentos para o tratamento da disfunção erétil são a tadalafila (Cialis), a vardenafila (Levitra, Vivanza) e mais recentemente a avanafila (Spedra, Stendra). A sildenafila é usada principalmente para o tratamento da disfunção erétil. Ao atuar como um inibidor do PDE-5, permite que o GMPc seja mantido mais tempo em circulação (substância responsável pelo relaxamento dos músculos do pénis), o que leva a um maior aporte de sangue e consequentemente à ereção. Assim como para disfunção erétil, o citrato de sildenafila também é eficiente na doença rara chamada hipertensão arterial pulmonar (HAP ou PAH). Each film-coated tablet contains 100 mg Sildenafil (as sildenafil citrate). Excipient with known effect: Each 50 mg film-coated tablet contains 7.3 mg lactose monohydrate. Sildenafil is indicated in adult men with erectile dysfunction, which is the inability to achieve or maintain a penile erection sufficient for satisfactory sexual performance. In order for Sildenafil to be effective, sexual stimulation is required. Use in adults The recommended dose is 50mg taken as needed approximately one hour before sexual activity. Based on efficacy and tolerability, the dose may be increased to 100mg or decreased to 25mg. The maximum recommended dosing frequency is once per day. If Sildenafil is taken with food, the onset of activity may be delayed compared to the fasted state (see Section 5.2). Elderly Dosage adjustments are not required in elderly patients (≥ 65 years old).

    Sildenafil pah

    Sildenafil marketed as Viagra and Revatio Information, Sildenafil Revatio® - Pulmonary Hypertension Association

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  4. Sildenafil oral tablet is a prescription medication used to treat erectile dysfunction ED and pulmonary arterial hypertension PAH. It's available as generic drugs and as the brand-name drugs.

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    Learn about Viagra Sildenafil Citrate may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications. Medscape - Pulmonary hypertension, erectile dysfunction-specific dosing for Revatio, Viagra sildenafil, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. Group 1 PAH — Patients with group 1 pulmonary arterial hypertension PAH have idiopathic pulmonary arterial hypertension IPAH, formerly called primary pulmonary hypertension, hereditary PAH, or PAH due to diseases that localize to small pulmonary arterioles, such as connective tissue diseases, HIV infection, portal hypertension, congenital.

     
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