Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil nausea Hair loss plaquenil myositis Long-term effects of taking plaquenil Plaquenil ceftriaxone interaction These may occur for the first few days a person takes the drug while the body adjusts to the medication. Loss of appetite, tiredness, weakness, or headache are uncommon side effects and typically go away over time. Rare complications. The greatest concern people have when taking hydroxychloroquine is related to vision. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking Plaquenil and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. How long do you have to take hydroxychloroquine side effects Plaquenil Side Effects on Your Eyes and Vision, Plaquenil Uses, Dosage & Side Effects - Plaquenil for celiacChloroquine diphospahe bbguySide effects of taking plaquenilPlaquenil for autoimmune hepatitis Taking the medication for the full six months can help you make a decision about continuing it. Does Hydroxychloroquine Have Side Effects? Like all medications, there is the risk of side effects. Fortunately, the problems seen by people taking this medication are usually very mild. Serious side effects are rare. RA and Hydroxychloroquine How Effective is it for.. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. HYDROXYCHLOROQUINE - ORAL Plaquenil side effects, medical uses, and.. Serious side effects are rare. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness. Rarely, hydroxychloroquine can lead to anemia in some individuals. SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Does Hydroxychloroquine Have Side Effects? Like all medications, there is the risk of side effects. Fortunately, the problems seen by people taking this medication are usually very mild. Serious side effects are rare. Overall, most people who have any noticeable side effects from hydroxychloroquine experience diarrhea or nausea.