It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Hg wang chloroquine Chloroquine and bafilomycin Plaquenil and dizziness Plaquenil and joint repla To the Editor Chloroquine CQ and hydroxychloroquine HCQ are widely used in the longterm treatment of connective tissue disease CTD and are usually considered safe1. However, these therapies may cause serious adverse events2, including cardiac toxicity3. The cardiomyopathy induced by an antimalarial drug might mimic the cardiac involvement of Fabry disease FD, a genetic storage. Heart Failure and Cardiac Disease; Hypertension; Imaging and Diagnostic Testing; Intervention, Surgery, Transplantation; Quality and Outcomes; Stroke; Vascular Disease; Features. Emerging Investigators; Advances in Heart Failure; On My Mind; Images and Case Reports in Heart Failure; HF Waveforms; Resources & Education. AHA Guidelines and Statements We present a case of twin sisters who both suffered from systemic lupus erythematosus SLE and HCQ-induced cardiomyopathy presenting with decompensated heart failure HF, suggesting that genetic predisposition might be a factor in HCQ-induced cardiomyopathy. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Hydroxychloroquine induced cardiomyopathy and heart failure in twins Hydroxychloroquine-Induced Cardiomyopathy Case Report., Hydroxychloroquine-Induced Cardiomyopathy Circulation. Plaquenil help with fatigueChloroquine dose during pregnancyChloroquine resistant plasmodium falciparumCan you take plaquenil and cialis togetherEfectos de hydroxychloroquine Genetic predisposition for HCQ‐induced cardiomyopathy was first proposed in a set of twin sisters who both suffered from SLE. 9 Chatre et al. described a case of a 61‐year‐old woman whose diagnosis of α‐galactosidase A deficiency was unmasked by chronic HCQ treatment. 10 Because Fabry disease and other lysosomal storage disorders, such. Hypertrophic cardiomyopathy in a lupus patient a case of.. Hydroxychloroquine-induced cardiomyopathy and heart failure.. Hydroxychloroquine SpringerLink. Cardiomyopathy is a disease of the heart muscle, which causes it to become weakened and unable to pump blood effectively. Cardiomyopathy is a major cause of heart failure and one of the most common conditions leading to heart transplantation. There are three types of cardiomyopathy In dilated cardiomyopathy, the left ventricle becomes enlarged and does not pump as efficiently. In hypertrophic. Hydroxychloroquine and colchicine neuromuscular toxicity is well documented. The largest literature review on colchicine myopathy was conducted by Wilbur and Makowsky in 2004 where a database search found 75 cases. Most patients presented with proximal muscle weakness. A wide range of treatment durations were noted from 4 days to 11 yrs with cumulative daily doses of 1.4 ± 0.96 mg. The. Although the precise incidence is unknown, drug-induced myopathy is among the most common causes of muscle disease. Drug-induced myopathy ranges from mild myalgias with or without mild weakness to chronic myopathy with severe weakness and to massive rhabdomyolysis with acute renal failure.