While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. "Hydrochloroquine (Plaquenil) has been a blessing for me. Medication reaction rash to plaquenil New guidelines for plaquenil screening Plaquenil hydroxychloroquine "been taking Plaquenil for RA for around 6 months then about 3 weeks ago started having muscular pain, not as bad as the joint pain I used to have but enough to be concerned. muscle weakness, painful, as if I worked out for 2 hours praying it is a dosage problem" Do you still have joint and muscle pain on plaquenil? I've been on plaquenil for 6 months now and I still have significant joint pain! I can't say that the drug has helped at all, but it is difficult to compare todays pain with that of 6 months ago. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes. I do occasionally experience dry eyes and a little scalp itch but asserting that it's caused by Hydrochloroquine would be anecdotal at best. It took about 5 weeks to take effect but my RA is basically a non factor now. Pain worse after plaquenil When starting hydroxychloroquine do symptoms feel. - LUPUS UK, Lupus Do you still have joint and muscle pain on plaquenil? Plaquenil and borderline personality disorder When starting hydroxychloroquine do symptoms feel worse. got so ill they wanted me to go on chemo based drugs but I did not want that either. so reluctantly went back on the plaquenil. imo its made me worse. I hate it and now cant come off it but cannot bear the fibrio type pain it has given me. now they want me on a drug they use for. When starting hydroxychloroquine do symptoms feel.. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Stopping plaquenil. DailyStrength. Fast forward 4 more months, peripheral neuropathy was getting worse even on lower dose and fingers and toes were also aching now, constantly tingling and numbness would come and go. All blood work came back "normal", lupus is in remission/ inactive. Yay! Dr stopped Hydroxychloroquine plaquenil yesterday fearing it is now doing more harm than good. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. My knees and legs hurt, back, hips, shoulders, fingers, and now my left heel - which has me limping half the time. I felt the Plaquenil helped the fatigue, but it seems the pain is sabotaging that effect. It also stopped my hair loss and soon after starting it, the skin on my face became more normal and less coarse. I was thrilled.