Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil (hydroxychloroquine, Sanofi-Aventis) therapy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Although the incidence of macular toxicity is infrequent with Plaquenil use (at a dosage of 200mg or 400mg q.d.), its visual impact can be devastating. Can you take plaquenil with lipitor Chloroquine phosphate fish medication dosage Plaquenil cena Plaquenil cumulative dose If you feel like your central vision is getting blurred, if you lose the ability to see a digital clock, if you lose color vision—if reds look kind of washed out—or if you have trouble seeing at night Those are early signs that you might be developing Plaquenil retinopathy,” says Katz. Plaquenil hydroxychloroquine sulfate, Sanofi-Aventis and the less-used chloroquine are antimalarial drugs with anti-inflammatory properties that are used for the management of a spectrum of inflammatory conditions. Vision loss typically is permanent, with little significant improvement, and may continue to progress even years after drug cessation. Previous Plaquenil Testing Guidelines In 2002, the American Academy of Ophthalmology AAO established ocular examination guidelines for screening patients on Plaquenil therapy. Initially, central visual acuity may be unaffected, but the patient may notice related paracentral scotomas that often interfere with reading. The associated classic retinal toxicity is described as a bull’s eye maculopathy (ring of depigmented retinal pigment epithelium that spares the foveal area). Plaquenil and color vision Common and Rare Side Effects for Plaquenil Oral, How to Succeed in Plaquenil Screenings Plaquenil cognitive side effectsPlaquenil vaccinesPlaquenil throat painAralen priceChloroquine diphsophate Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking Plaquenil and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Plaquenil Uses, Dosage & Side Effects -. New Plaquenil Guidelines. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Decreased vision; Photopsias; Glare; Metamorphopsia; Paracentral scotomas; Decreased night vision; Decreased color vision; TREATMENT. No treatment to reverse chloroquine or hydroxychloroquine toxicity. Recommend cessation of the medication, but visual function rarely recovers, especially in the later stages of the disease. Although rare, Plaquenil can cause significant toxicity to the eye with prolonged use. Also, Plaquenil may have various systemic side effects that are not related to the eyes. These too are rare and include nerve weakness, hallucinations, psoriasis and changes in hair color. The eye complications are the most serious and worrisome. Patients with retinal changes may be asymptomatic initially, or may have scotomatous vision with paracentral, pericentral ring types, temporal scotomas, and abnormal color vision.-Corneal changes including edema and opacities can be symptomless or may cause disturbances such as haloes, blurring of vision or photophobia. They may be transient.