To date, it was assumed that chloroquine increases the sensitivity of cancer cells to chemotherapy by means of a direct effect on the cancer cells. However, a recent study has demonstrated that chloroquine also normalizes the abnormal blood vessels in tumors. Where to order plaquenil Atrovent and plaquenil Hydroxychloroquine sulfate plaquenil side effects Hydroxychloroquine withdrawal symptoms Chloroquine diphosphate CQ, a worldwide used anti-malarial drug, has recently been focused due to its potential biological effects on cancer cells, such as the inhibition of cell growth and/or induction of cell death in human lung cancer A549 cells, glioma cells, human breast cancer cells, and mouse colon cancer CT26 cells, resulting in anti-cancer effects 3-7. This medicine may add to the chance of getting some types of cancer. Talk with the doctor. Keep away from children. Accidental exposure may cause death. If a child takes chloroquine by accident, get medical help right away. If you are 65 or older, use chloroquine with care. You could have more side effects. Chloroquine sensitizes breast cancer cells to chemotherapy independent of autophagy The anti-cancer effect of the antimalarial agent chloroquine when combined with conventional chemotherapy has been well documented in experimental animal models. This blood vessel normalization results in an increased barrier function on the one hand, and in enhanced tumor perfusion on the other hand, which increases the response of the tumor to chemotherapy. Chloroquine and breast cancer Chloroquine Inhibits Autophagy to Potentiate Antiestrogen., Chloroquine Indications, Side Effects, Warnings - Is chloroquine an anitbioticPlaquenil drugs com Find patient medical information for Chloroquine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Chloroquine Oral Uses, Side Effects, Interactions, Pictures.. Chloroquine sensitizes breast cancer cells to chemotherapy.. Definition of chloroquine - NCI Drug Dictionary - National Cancer Institute. Chloroquine CQ is a well known, well tolerated medication that has been used for many years traditionally for arthritis, lupus, and malaria. It has anti-inflammatory properties but is often the drug of choice for arthritis and malaria due to its few side effects. The anti-malarial chloroquine overcomes Primary resistance and restores sensitivity to Trastuzumab in HER2-positive breast cancer Skip to main content Thank you for visiting The antimalarial drugs chloroquine CQ and hydroxychloroquine HCQ have potential applications in cancer treatment. The growth of MCF-7 and MDA-MB-231 human breast cancer cells in vitro was inhibited by CQ and HCQ and these cells were more sensitive than nontumorigenic MCF-10A breast epithelial cells.