Im chloroquine

Discussion in 'Hydroxychloroquine Plaquenil' started by DBD, 28-Feb-2020.

  1. Jorge Grey New Member

    Im chloroquine


    -Suppressive therapy should continue for 8 weeks after leaving the endemic area. Approved indication: For the suppressive treatment of malaria due to Plasmodium vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: 300 mg base (500 mg salt) orally once a week Comments: -For prophylaxis only in areas with chloroquine-sensitive malaria -Prophylaxis should start 1 to 2 weeks before travel to malarious areas; should continue weekly (same day each week) while in malarious areas and for 4 weeks after leaving such areas.

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    Although widely considered dangerous, parenteral chloroquine is extensively used. We studied the acute disposition and toxicity of intravenous iv, intramuscular im, subcutaneous sc, and oral chloroquine in 60 adult Zambian patients hospitalized with falciparum malaria. Chloroquine is a 4-aminoquinolone compound with a complicated and still unclear mechanism of action. It is believed to reach high concentrations in the vacuoles of the parasite, which, due to its alkaline nature, raises the internal pH. Chloroquine is used to prevent or treat malaria caused by mosquito bites in countries where malaria is common. Malaria parasites can enter the body through these mosquito bites, and then live in.

    Approved indication: For acute attacks of malaria due to P vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: Chloroquine-sensitive uncomplicated malaria (Plasmodium species or species not identified): 600 mg base (1 g salt) orally at once, followed by 300 mg base (500 mg salt) orally at 6, 24, and 48 hours Total dose: 1.5 g base (2.5 g salt) Comments: -For the treatment of uncomplicated malaria due to chloroquine-sensitive P vivax or P ovale, concomitant treatment with primaquine phosphate is recommended. 60 kg or more: 1 g chloroquine phosphate (600 mg base) orally as an initial dose, followed by 500 mg chloroquine phosphate (300 mg base) orally after 6 to 8 hours, then 500 mg chloroquine phosphate (300 mg base) orally once a day on the next 2 consecutive days Total dose: 2.5 g chloroquine phosphate (1.5 g base) in 3 days Less than 60 kg: First dose: 16.7 mg chloroquine phosphate/kg (10 mg base/kg) orally Second dose (6 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Third dose (24 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Fourth dose (36 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Total dose: 41.7 mg chloroquine phosphate/kg (25 mg base/kg) in 3 days Comments: -Concomitant therapy with an 8-aminoquinoline compound is necessary for radical cure of malaria due to P vivax and P malariae.

    Im chloroquine

    Chloroquine Oral, Intramuscular Advanced Patient Information -, Antimalarial medication - Wikipedia

  2. Plaquenil pros and cons
  3. Education and information regarding choosing a drug to prevent malaria, including a list of all available drugs and reasons for taking or not taking a certain drug.

    • CDC - Malaria - Travelers - Choosing a Drug to Prevent Malaria.
    • Chloroquine Oral Uses, Side Effects, Interactions..
    • Chloroquine-induced Pruritus - PubMed Central PMC.

    Chloroquine is an anti-malarial drug available at pharmacies for people traveling to area with malaria risks. Note based on a RGCC chemosensitivity analysis I have seen at a German clinic, Hydroxychloroquine has been effective in killing the cancer cells of 5 out 7 patients that were tested. Chloroquine resistance was found in the only case of Plasmodium falciparum malaria. Chloroquine is absorbed rapidly after divided dose intramuscular injection and single dose subcutaneous injection and does not cause hypotension or neurotoxicity in adults. Antimalarial action Chloroquine binds to DNA, interfering with protein synthesis. It also inhibits DNA and RNA polymerases.

     
  4. mvlad XenForo Moderator

    Chloroquine is used to prevent or treat malaria caused by mosquito bites in countries where malaria is common. Chloroquine Oral Uses, Side Effects, Interactions. Side Effects of Malarone Atovaquone and Proguanil Hcl. Chloroquine vs Hydroxychloroquine Comparison -
     
  5. Yaneck New Member

    , including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods. Aralen Tablets Manufacturer from Vadodara Antibacterial * Trimox, Bactrim, Suprax, Aralen, Ceftin. CDC - Malaria - Travelers - Choosing a Drug to Prevent Malaria
     
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  7. zernoopt Well-Known Member

    Hydroxychloroquine plaquenil withdrawl? - LUPUS UK With the Plaquenil I don't think you will find much relief in such a short time on it & at half of a workable dose. I have read about people stopping P & flaring up. Those who stopped it abruptly had real problems similar to what you are experiencing. If you really need to get off it, I would taper down slowly, very slowly.

    Plaquenil Withdrawal – Life As An Anomaly