I've been on plaquenil for 6 months for suspected Sjogren's syndrome (I don't have antibodies for Sjorgren's or Lupus but I do have Hashimoto's and have all the symptoms for Sjorgren's so the rheumatologist suggested a trial of plaquenil). Basically I've been on the drug since January and saw the rheumatologist on Wednesday to see how things are going. Plaquenil cause low wbc Take plaquenil while healing leaky gut Relapse of plasmodium vivax after chloroquine Plaquenil skin cancer Plaquenil Arthritis Information. Share. Have any of you gone off this drug and had side affects from going off like hurting ribs, hips, feet, fingers, It is terribe so I went back on it today. They also are decreasing my predisone 5 mg every 2 weeks. Nov 14, 2006 Lupians, from the lupus forum, warned me of plaquenil withdrawl, which I guess leads to rebound arthritis, a particularly severe form that occurs when coming down off one of the DMARDs, or even off of prednisone for that matter. Been on Plaquenil only for ten years for sarcoidosis. Once in awhile I also had to have a burst of prednisone. I have been weaning off since my sarcoidosis has been stable for eight years. I went from 400 mg. Daily to 200 daily to 200 every other day over the course of six months. I stopped it about 10 days ago and I feel like I’m 90 years old. I do think it's helped with fatigue and muscle pain but it's hard for me to compare to Xmas as when the improvement is so gradual I think it's really hard to notice on a gradual basis. I *think* I'm improving but it's been a gradual process and I said to him that it's quite hard to tell how much of an improvement I'm feeling. Weaning off of plaquenil Weaning off Flecainide - American Heart Association, Plaquenil - Does plaquenil effect healing after surgeryPlaquenil menstruation disturbanceHydroxychloroquine glovesDoes plaquenil prevent malariaKinetics of chloroquine Hi honey, YES.stopping plaquenil for a couple of days can cause symptoms to arise or get worse.needs to be taken exactly as prescribed. Twice a day, every day. Missing one dose wont make a major difference but skipping more then one, or days absolutely can. Stopping plaquenil. DailyStrength. Plaquenil Withdrawal – Life As An Anomaly. Let me tell you what weaning down from Plaquenil is like.. Withdrawal syndrome is found among people who take Plaquenil, especially for people who are female, 50-59 old also take medication Lyrica, and have Fibromyalgia. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA, and is updated regularly. The lower the dosage of steroids, the better for the patient. You may be given a steroid medication at first to help reduce the lupus symptoms until the time that the Plaquenil begins to take effect, which, as we mentioned, can take several months. Some drugs that may interact with Plaquenil antacids; botulinum toxins; digoxin; kaolin Check with your doctor right away if you or your child have any of the following symptoms while using this medicine blistering, peeling, or loose skin, red skin lesions, severe acne or skin rash, sores or ulcers on the skin, or fever or chills while you are using this medicine.