Plaquenil and diabetic retinopathy

Discussion in 'Northwest Pharmacy Canada' started by karlitto, 28-Feb-2020.

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    Plaquenil and diabetic retinopathy


    She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine (Plaquenil) 200mg bid (6.5mg/kg) for 10 years, which was stopped one year prior to presentation.

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    Hydroxychloroquine HCQ is an antimalarial agent that is commonly used to treat rheumatoid arthritis RA and systemic lupus erythematosus SLE. The present report documents a case of hypoglycaemia due to HCQ in a patient with SLE and diabetes mellitus type 2, in which the HCQ completely replaced the need for daily subcutaneous insulin. A study of 12 patients with hydroxychloroquine retinopathy and 103 patients being treated with hydroxychloroquine but without retinopathy reported a sensitivity of 85.7% for 10–2 VFA and 78.6% for SD-OCT, and specificities of 92.5% and 98.1%, respectively. HealthDay—Hydroxychloroquine HCQ blood levels are useful in predicting retinopathy among patients with systemic lupus erythematosus SLE, according to a study published online Sept. 18 in.

    Review of systems: Blurred vision, halos, dry eye, dry mouth, gastroesophageal reflux, joint pain Pupils: Reactive to light in each eye from 5 mm in the dark to 2 mm in the light. Extraocular movements: Full, both eyes (OU) Confrontation visual fields: Full OU Intra-ocular pressure The optic nerves appeared healthy with a 0.3 cup-to-disc ratio. Past Ocular History: None Medical History: Sjogren syndrome and inflammatory arthritis, supraventricular tachycardia, anxiety, depression, peptic ulcer disease Medications: prednisone, methotrexate, amitriptyline, ranitidine, estradiol, tizanidine, diltiazem, Restasis Allergies: codeine, droperidol Family History: heart disease, arthritis, cancer Social History: occasional alcohol but no tobacco or intravenous drug use.

    Plaquenil and diabetic retinopathy

    Retinal Physician - Hydroxychloroquine Maculopathy An., Hydroxychloroquine retinopathy — implications of research.

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  7. Hydroxychloroquine oral tablet is available as a brand-name drug and a generic drug. Brand name Plaquenil. Hydroxychloroquine comes only as a tablet you take by mouth. Hydroxychloroquine is used to treat malaria, lupus erythematosus, and rheumatoid arthritis.

    • Hydroxychloroquine Side Effects, Dosage, Uses, and More.
    • Hydroxychloroquine blood levels predict retinopathy risk..
    • Retinopathy Guide Causes, Symptoms and Treatment Options.

    With diabetes, the blood vessels supplying the retina and other parts of the eye become fragile and compromised. The retinopathy related to plaquenil use is actually from a kind of deposit that forms on the surface of the retina and in advanced cases, takes a "bulls-eye" shape that can be seen on exam. For those of you that don't know, plaquenil can cause a certain kind of retinopathy/maculopathy in the eyes if your dose is too high because the drug builds up in your system. It can cause blindness. So when I had the photography done the optometrist had a concerned look on her face and proceeded to take 17 more photos of my retinas. Johnson and Vine examined nine patients taking a cumulative dose of hydroxychloroquine of greater than 1,000 g and noted that eight patients taking 400 mg/d had no evidence of retinopathy, whereas one patient taking more than 600 mg/d had retinopathy. 5 Bernstein concurred with this study, but noted that patients with chronic renal.

     
  8. Dilman Moderator

    Long-term malaria prophylaxis is hampered by a lack of standardization and compliance. Chloroquine - FDA prescribing information, side effects and uses Chloroquine - an overview ScienceDirect Topics WHO Model Prescribing Information Drugs Used in Parasitic.
     
  9. msoleg New Member

    Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. What is the correct way to discontinue use of plaquenil? Hydroxychloroquine MedlinePlus Drug Information Drug tapering An option, not a necessity, for patients with.
     
  10. allsubmitter10k New Member

    Current and emerging pharmacological treatments for. Apr 12, 2013 The treatment of sarcoidosis is not standardized. It is primarily driven by the effect of sarcoidosis upon the patient’s symptoms and quality of life. In a large percentage of sarcoidosis patients, treatment is not indicated. Corticosteroids are the drug of choice for most forms of sarcoidosis.

    Sarcoidosis Treatment & Management Medical Care, Surgical.
     
  11. b84 Well-Known Member

    PLAQUENIL® - Food and Drug Administration Cardiomyopathy has been rarely reported with high daily dosages of hydroxychloroquine. Dosage and Administration One tablet of 200 mg of hydroxychloroquine sulfate is equivalent to 155 mg base. Malaria Suppression— In adults, 400 mg =310 mg base on exactly the same day of each week.

    Plaquenil dosage Hi there, been on plaquenil for.