Prandin dosage

Discussion in 'Pharmacy Tech' started by Samedi, 05-Sep-2019.

  1. n01038 User

    Prandin dosage


    Repaglinide is used alone or with other medications to control high blood sugar along with a proper diet and exercise program. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. It works by stimulating the body to produce more insulin. Insulin is a natural substance that allows the body to properly use sugar from the diet. Read the Patient Information leaflet if one is available from your pharmacist before you start using repaglinide and each time you get a refill. If you have any questions, consult your doctor or pharmacist. Take this medication by mouth within 30 minutes before each meal as directed by your doctor, usually 2-4 times daily depending on the number of meals. Hypersensitivity to repaglinide Diabetic ketoacidosis Type I diabetes mellitus Coadministration of gemfibrozil results in increased repaglinide plasma concentration (8-fold increase); may lead to severe hypoglycemia Stress due to infection, fever, trauma, or surgery; may need to discontinue if exposed to stress Hepatic/renal insufficiency Patients at risk of severe hypoglycemia: Elderly, debilitated, or malnourished; adrenal or pituitary insufficiency Myocardial ischemia reported in patients treated concomitantly with NPH-insulin; not indicated for use in combination with NPH-insulin Use caution in elderly and malnourished patients Pregnancy or lactation The use of sulfonylureas may be associated with increased cardiovascular events Drugs that inhibit organic anion transporting protein OATP1B1 (eg, cyclosporine) may increase plasma concentrations of repaglinide, which is a substrate for active hepatic uptake transporter OATP1B1 Limited available data from case reports and case series have not identified a drug-associated risk of major birth defects, miscarriage or adverse maternal, or fetal outcomes in women taking repaglinide while pregnant Detected in breast milk of rat dams and lowered blood glucose levels were observed in the pups Cross fostering studies indicated that skeletal changes could be induced in control pups nursed by treated dams, although this occurred to a lesser degree than those pups treated in utero Increases insulin secretion by blocking ATP potassium channels on beta islet cells, which facilitates calcium entry through calcium channels; increased intracellular calcium stimulates insulin release from pancreatic beta cells Take dose 15 minutes before meal May be dosed 2, 3, or 4 times a day in response to changes in meal pattern Skipped meals: Instruct patients to skip the scheduled repaglinide dose to reduce the risk of hypoglycemia The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

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    Medscape - Diabetes mellitus type 2 dosing for Prandin repaglinide, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. In a double-blind, placebo-controlled, 3-month dose titration study, PRANDIN or placebo doses for each patient were increased weekly from 0.25 mg not an approved dose through 0.5, 1, and 2 mg, to a maximum of 4 mg, until a fasting plasma glucose FPG level 160 mg/dL was achieved or the maximum dose reached. Patients should administer PRANDIN before meals and be instructed to skip the dose of PRANDIN if a meal is skipped. In patients who experience hypoglycemia, the dose of PRANDIN should be reduced see DOSAGE AND ADMINISTRATION. Patients and caregivers must be educated to recognize and manage hypoglycemia.

    DOSAGE AND ADMINISTRATION There is no fixed dosage regimen for the management of type 2 diabetes with PRANDIN. The patient's blood glucose should be monitored periodically to determine the minimum effective dose for the patient; to detect primary failure, i.e., inadequate lowering of blood glucose at the maximum recommended dose of medication; and to detect secondary failure, i.e., loss of an adequate blood glucose-lowering response after an initial period of effectiveness. Glycosylated hemoglobin levels are of value in monitoring the patient's longer term response to therapy. Short-term administration of PRANDIN may be sufficient during periods of transient loss of control in patients usually well controlled on diet. PRANDIN doses are usually taken within 15 minutes of the meal but time may vary from immediately preceding the meal to as long as 30 minutes before the meal. When beginning Prandin, the dosage you are prescribed will depend on your hemoglobin A1c (Hb A1c) result. If your Hb A1c is less than 8 percent, the starting dose is Prandin 0.5 mg, taken before each meal. If your Hb A1c is higher, the starting dose is Prandin 1 mg or Prandin 2 mg, taken before each meal. Hb A1c is a test often used to measure long-term blood sugar control in people with diabetes. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click In order for us to create your customized Health Savvy programs, we need a little more information about the health topic(s) that you are interested in. Press "Continue" button below to begin selecting your Health Savvy topic(s). Remember, you need at least one selected topic to use Health Savvy.

    Prandin dosage

    Prandin Oral Uses, Side Effects, Interactions, Pictures., DailyMed - PRANDIN- repaglinide tablet

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  7. The recommended dose range is 0.5 mg to 4 mg taken with meals. PRANDIN may be dosed preprandially 2, 3, or 4 times a day in response to changes in the patient’s meal pattern. The maximum recommended daily dose is 16 mg.

    • Prandin Dosage Guide -.
    • Prandin Repaglinide Side Effects, Interactions, Warning..
    • Prandin Dosage - Diabetes Home Page.

    Repaglinide lowers blood glucose by encouraging your pancreas to produce more insulin. It works quickly so is particularly helpful in. PRANDIN prescription and dosage sizes information for physicians and healthcare professionals. Pharmacology, adverse reactions, warnings and side effects. MEGLITINIDE DOSING. All dosing is for ADULTS unless otherwise specified. MEGLITINIDES. Nateglinide Starlix® Repaglinide Prandin®. COMBINATION.

     
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