Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Plaquenil and liver enzymes Smoking and plaquenil Chloroquine resistant p falciparum Low-dose hydroxychloroquine in treatment of porphyria My rheumy has just prescribed Plaquenil for my SS. Reading the warnings, I see that there is concern about effects on the eyes retinas. I am very concerned about this and am wondering if anyone out there has been put on an alternative drug to treat their SS. I have several issues with my. May 07, 2019 Plaquenil hydroxychloroquine is commonly used to help keep mild lupus-related problems, such as skin and joint disease, under control. This drug is also effective at preventing lupus flares. The Lupus Foundation of America. American College of Rheumatology. May 20, 2008 Because the action of Plaq isn't really understood in SjS, and it's a unique classification of drug in treating AIs, there really isn't a substitute for it, but there are other classes of drugs, also called DMARDS disease modifying anti-rheumatic drugs that are also used. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Substitutes for plaquenil Plaquenil Oral Uses, Side Effects, Interactions, Pictures., How is plaquenil hydroxychloroquine used to treat lupus? Plaquenil and multivitaminsDoes plaquenil effect healing after surgeryPlaquenil optometry examPlaquenil somnolence Nothing safer Plaquenil is also known as hydroxychloroquine, so the parent drug Chloroquine can be substituted. But Chloroquine has significantly higher rate of retinal toxicity, so it isn't used much anymore. Also, Plaquenil appears to effectively reduce flares in patients with lupus not necessarily by suppressing immunity. Plaquenil substitute - Things You Didn’t Know. Is there an alternative to Plaquenil? - Sjogren's World. Hydroxychloroquine Plaquenil. Three anti-malarial drugs are prescribed for lupus symptoms. Hydroxychloroquine Plaquenil is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine Aralen has a reputation for more serious side effects. COMMON BRAND NAMES Plaquenil. Uses. This medication is used to treat rheumatoid arthritis and lupus; and to treat or prevent malaria. How To Use. Take this medication with food to prevent stomach upset. Take this medication exactly as prescribed. Do not stop taking it without consulting your doctor. I "know" I need some meds, but cannot tolerate Plaquenil. Wondering if anyone has come across something "natural" that mimics it. Thanks & LIGHT*****carole - Hi, Carole. When I started Plaquenil, my GI system was in an uproar. But it usually was anyway. I didn't realize, until I saw Dr.